{"title":"Radiology","description":"","products":[{"product_id":"definity","title":"Definity","description":"\u003cp\u003eDEFINITY® is indicated, after activation, for use in adult and pediatric patients with suboptimal echocardiograms to opacify the left ventricular chamber and to improve the delineation of the left ventricular endocardial border.\u003c\/p\u003e\n\u003cp\u003eIMPORTANT SAFETY INFORMATION\u003cbr\u003eBOXED WARNING: SERIOUS CARDIOPULMONARY REACTIONS\u003cbr\u003eSerious cardiopulmonary reactions, including fatalities, have occurred uncommonly during or following perflutren-containing microsphere administration. Most serious reactions occur within 30 minutes of administration.\u003cbr\u003eAssess all patients for the presence of any condition that precludes DEFINITY® administration.\u003cbr\u003eAlways have resuscitation equipment and trained personnel readily available.\u003c\/p\u003e\n\u003cp\u003eCONTRAINDICATIONS:\u003cbr\u003eContraindicated in patients with known or suspected hypersensitivity to perflutren lipid microsphere or its components, such as polyethylene glycol (PEG).\u003c\/p\u003e\n\u003cp\u003eWARNINGS AND PRECAUTIONS:\u003cbr\u003eSerious Cardiopulmonary Reactions have occurred during or following administration. The risk for these reactions may be increased among patients with unstable cardiopulmonary conditions (acute myocardial infarction, acute coronary artery syndromes, worsening or unstable congestive heart failure, or serious ventricular arrhythmias).        \u003c\/p\u003e\n\u003cp\u003eSerious Hypersensitivity Reactions have been observed during or shortly following administration including anaphylaxis, with manifestations that may include death. DEFINITY contains PEG and may increase risk of serious reactions including death in patients with prior hypersensitivity reaction(s) to PEG. Clinically assess patients for prior hypersensitivity reactions to products containing PEG. Monitor all patients for hypersensitivity reactions.         \u003c\/p\u003e\n\u003cp\u003eSystemic Embolization may occur in patients with a cardiac shunt. Assess patients with shunts for embolic phenomena following administration. DEFINITY is only for intravenous administration and must not be administered by intra-arterial injection.        \u003c\/p\u003e\n\u003cp\u003eThere is a risk of Ventricular Arrhythmia Related to High Mechanical Index. Additionally, end-systolic triggering with high mechanical indices has been reported to cause ventricular arrhythmias. The maximum recommended mechanical index for use with DEFINITY is 0.8 in adult patients and 0.3 in pediatric patients.         \u003c\/p\u003e\n\u003cp\u003eAcute Pain Episodes in Patients with Sickle Cell Disease (SCD) shortly following administration have been reported. Discontinue DEFINITY in SCD patients experiencing new or worsening pain.\u003c\/p\u003e\n\u003cp\u003eADVERSE REACTIONS:\u003cbr\u003eThe most common adverse reactions (≥0.5%) are headache, back\/renal pain, flushing, nausea, chest pain, injection site reactions, and dizziness.         \u003c\/p\u003e\n\u003cp\u003eYou are encouraged to report negative side effects of prescription drugs to the FDA. Visit MedWatch or call 1-800-FDA-1088.        \u003c\/p\u003e\n\u003cp\u003ePlease see the accompanying full Prescribing Information and important safety information, including BOXED WARNING for serious cardiopulmonary reactions. \u003c\/p\u003e\n\u003cp\u003eReferences:\u003c\/p\u003e\n\u003cp\u003eDEFINITY®. Prescribing Information. Lantheus.\u003cbr\u003eData on file, Volume since launch, Lantheus. 2025.\u003cbr\u003eData on file, Historical procedures, Lantheus. 2024.\u003cbr\u003eData on file, Published literature, Lantheus. 2024.\u003cbr\u003ePorter TR, Mulvagh SL, Abdelmoneim SS, et al. Clinical applications of ultrasonic enhancing agents in echocardiography: 2018 American Society of Echocardiography guidelines update. J Am Soc Echocardiogr. 2018;31(3):241-274. doi:10.1016\/j.echo.2017.11.013\u003c\/p\u003e\n\u003ch5\u003ePRESCRIBING INFORMATION\u003c\/h5\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/1750\/9895\/files\/Definity-US-PI-515987-1017.pdf?116\" title=\"Definity Prescribing Information\" rel=\"noopener noreferrer\" target=\"_blank\"\u003eDefinity Prescribing Information\u003c\/a\u003e\u003c\/p\u003e","brand":"Lantheus","offers":[{"title":"Default Title","offer_id":22508001689718,"sku":null,"price":0.0,"currency_code":"AUD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1750\/9895\/products\/Definity_Vial_Main.png?v=1554706148"}],"url":"https:\/\/www.globalmedicalsolutions.com.au\/collections\/radiology-1.oembed","provider":"GMS Australia Pty Ltd","version":"1.0","type":"link"}